Think Outside the Rectangle

Nutanix Enterprise Cloud on HPE® ProLiant®

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The Leading Enterprise Cloud Software
is available on
The Most Widely Deployed Enterprise Server

HPE® ProLiant® servers are fully tested and certified by Nutanix to run Nutanix Enterprise Cloud software. HPE® customers are able to leverage Nutanix solutions to build an enterprise cloud delivering the simplicity and agility of public cloud services, with the control and security needed in private cloud environments. ProLiant® customers receive the same Nutanix compute, storage, virtualization and network functionality – plus the company’s intuitive, consumer-grade management that has made Nutanix the industry’s most popular hyperconverged solution.

Nutanix on ProLiant® in 30 Seconds

  • Build a full infrastructure stack with just HPE® ProLiant® servers and Nutanix Enterprise Cloud software.
  • Eliminate expensive and complex SANs and simplify your datacenter using ProLiant® server storage resources.
  • Radically simplify infrastructure management with one-click software upgrades, infrastructure scaling and troubleshooting – freeing IT staff to focus on business applications rather than the infrastructure.
  • Start small and scale your infrastructure without limits by adding ProLiant® servers one at a time.
  • Cut the cost of virtualization with the Nutanix native AHV hypervisor and integrated virtualization management.
  • Easily add Nutanix Enterprise Cloud software to your ProLiant® server with no change to your architecture or operations.

The Definitive Guide To Hyperconverged Infrastructure for HPE® ProLiant®

Get an inside look at the Nutanix Enterprise Cloud Platform and how it works on HPE® ProLiant®, including information on the difference between Nutanix and other hyperconverged offerings like SimpliVity® on ProLiant®.

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Comparing Nutanix on ProLiant® vs. SimpliVity® on ProLiant®

 NutanixHPE® SimpliVity®
Maximum Cluster SizeNutanixUnlimitedHPE® SimpliVity®8 servers
100% Software SolutionNutanixYesHPE® SimpliVity®No – requires proprietary FPGA card and HW RAID
Multiple Hypervisor Support and Integrated VirtualizationNutanixYes -
Hyper-V (no license cost for AHV)
HPE® SimpliVity®No – ESXi only and incurs a separate hypervisor license cost
1-Click Software UpgradesNutanixYesHPE® SimpliVity®No
Self-service Software UpgradesNutanix100% customer drivenHPE® SimpliVity®Limited
Data Locality and Relocalization for Optimal PerformanceNutanixYesHPE® SimpliVity®No

Which HPE® ProLiant® Models are Qualified?


1U rack server
Up to 8 small form factor (SFF) drive bays
All-flash configuration or hybrid option
2x SSD & up to 6x HDDs
Best For: VDI, Middleware, Web Services

DL380-G9 12LFF

2U rack server
Up to 12 larger form factor (LFF) drive bays
Hybrid configuration
2x SSD & up to 10x HDDs
Best For: Storage Heavy and Server Virtualization Workloads

DL380-G9 24SFF

2U rack server
Up to 24 SFF drive bays
All-flash configuration or hybrid option
4x SSD & up to 20x HDDs
Best For: MS Exchange, SQL and Large Databases

Nutanix on HPE® ProLiant® Best Practices Guide

These best practices walk you through key system design issues, from procurement to configuration and deployment.

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How is Nutanix on HPE® ProLiant® Supported?

Nutanix provides first call support for the complete HPE® ProLiant® hardware + Nutanix software solution.

Nutanix addresses all software-related issues, and proactively coordinates HPE® hardware support cases through TSANet (Technical Support Alliance Network –, which then hands off to HPE® for hardware support and replacement.

Customers get a single point of contact for all issues, and benefit from Nutanix’s unmatched 90+ Net Promoter Score (NPS).

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Strong Customer and Partner Demand

Nutanix’s support for HPE® ProLiant® is in response to strong demand from customers and channel partners. Authorized distributors and resellers for HPE® and Nutanix will integrate the HPE® hardware and Nutanix software either at their facilities or at the customer site. IT professionals get the same delightful experience as other all other Nutanix-supported hardware platforms.

Customers are able to purchase a Nutanix software entitlement, including Nutanix support services, through an authorized Nutanix channel partner, and obtain ProLiant® hardware and hardware support from HPE® or an authorized HPE® channel partner.

Are you an HPE customer or sales representative and would like more information?  Please let us know how we can help.

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HPE® and ProLiant® are registered trademarks of Hewlett-Packard Development LP and/or its affiliates.  Nutanix is not associated with, sponsored or endorsed by Hewlett-Packard.